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My mice are located in their own room of our home with the exception of the 75 gallon tank which is located in the living room. The mousery room is on the main floor of the house, in a spare bedroom. The door is almost always open so that it keeps good air flow. However, there is a baby gate that keeps those out that we don't want entering (dog, child, etc). The mice are on open air shelves to keep good airflow in their tanks.
Elements.
My mousery is kept between 70*F and 77*F at the extremes. It generally stays tight to 72*F year round with no possible cool draft. I have fish tank thermometers on several tanks spread through the mousery as well as a couple thermometers on the shelving units themselves. These are carefully watched. Windows are covered with light window treatments which screen the sunlight for harmful rays and dim any extreme light that could bake the mice. They still allow some natural and indirect (not touching the tanks) light in the mousery which helps keep the mice healthy. Sunlight provides vitamin D which helps bone health and prevention of autoimmune diseases, cancers, etc (it does not have to touch the mice to have positive effects). The windows in the mousery are fairly new and of good quality to keep out draft. As an added precaution I put a blanket around the shelf closest to the windows. I highly doubt it is needed, but I like to eliminate all potential risks I can. We have April Air which regulates humidity in the entire house, including the mousery. When the temperature and humidity outside is the same as it is inside, the windows in the mousery are opened to give them fresh air. There are 2 windows in the mousery which provides nice air flow. When there is no breeze outside, I place a window fan up to bring the outside air in. The mice very much enjoy this, often coming out to play. The lights in the mousery are set on a timer. They come on at 8am and turn off at 11pm. This gives them 9 hours of complete darkness and 15 hours of light. I keep them in light for this long because it enhances breeding productivity. Less light can make their body think that it's winter and breeding might not be as productive. There are no televisions or TV type computer monitors in the mousery. This is to keep out the high pitched squeal that those things can put out, potentially harming the hearing of the mice. The critter cams use a flat panel monitor which does not emit these sounds.
Exposure to other animals and surroundings.
In addition to the mice there are 2 adults, 1 child, 1 dog, and 2 cats that live in our home. The dog is not allowed in the mousery and a gate is put up to keep her out. She would never intentionally hurt any mouse, nor would she try to get one out of a cage (she would accidentally hurt one by playing if it was out though). We keep her out mainly because she likes to eat mouse food which upsets her tummy. The cats are allowed in the mousery when I'm there. However, the baby gate keeps our larger cat out. Our smaller cat (she's tiny like a kitten) doesn't have a desire to do much in there at all and couldn't do harm even if she tried. The mice don't care about the cats and will not bat an eyelash at them when the cats are watching them. I feel that cats in the mousery are good exposure to the mice. It gets them used to other animals so they will not freak out if they are adopted to a home with cats. The cats are indoor only. If the proper safety measures are taken, cats and mice can live under the same roof with no problems. Our toddler is allowed in the mousery when supervised. The mice are well used to al the sounds that toddlers make. I feel that exposure to young children helps the mice get used to company of different ages. This way adoptable mice will not be upset if they are adopted to a home with children. My mice are used to a female voice (such as mine) as well as the deep voice of a man (my husband). I also play a radio in my mousery which is playing constantly. The radio is set at a even level, not too loud and not too soft. The station my mice listen to is a variety of all kinds of music as well as talk in the AM. This helps expose mice to different types of noise. These things may seem insignificant but all of these exposures work wonders with taming mice. Mice that are not used to something will often be frightened of it. If they are exposed to a lot, in a safe manner, they will be more tame and will easily adjust to many different surroundings. Doing these things helps the mice as well as their adopter.
Cleaning
Housing units are cleaned on a weekly basis without fail. They are also cleaned during the week as needed. All plastic houses, toys, wheels, food dishes, etc are cleaned in a dedicated dishwasher (used only for mouse belongings) with a mild dishwashing detergent. The dishwasher is not located in the mouse room. I have between 70 and 130 mice at any given time. It generally takes 3+ loads to wash all of their possessions. I have duplicates of almost everything so no mouse goes without while their possessions are being cleaned. All wood is washed by hand in hot water, rinsed well, air dried, and often with the help of a fan directed at them. While cleaning the tanks/large kritter keepers the mice are either placed into a play tank with toys to play on or on my shoulder while they wait. Pregnant or nursing moms have their own dedicated play area, separate from the general play area, as I like to keep that even more regulated. All bedding is dumped at least once a week. Tanks and keepers are thoroughly wiped out with natural, unscented baby wipes and then dried with a paper towel. If they are bad I scrub them with antibacterial, unscented, Soft Soap in the bathtub. In addition, tanks and keepers are washed in the tub periodically whether they are bad or not (generally they are not bad because of how often they are cleaned). Quality baby wipes do not leave a residue but it's nice to give a good scrubbing now and then. After a tank or keeper is completely dry, all bedding, food, toys, houses, etc are replaced. Old water is dumped and replaced. My mice get purified water in their water bottle. It takes all day to clean everyone. If I tried to push through it quickly, it would probably only take half of a day (5-6 hours) but I like to spend added time with each as they are being cleaned so it generally takes me 1 1/2 days. No type of air freshener, candles, smoke, etc are ever used anywhere near my mousery. Mice have sensitive lungs and those things put mice at risk. In the mousery there is a True Air system which helps keep the air clean. Filters are cleaned/changed regularly.
Bedding
I use mixed bedding. I give my mice a bottom layer of Diamond Soft made by Teklad. This is an extremely soft, yet not overly fluffy (to help prevent impaction that some other beddings have a higher risk for). It is a specially-processed bleached hardwood paper pulp bedding that is completely scentless. It is pure white, completely dust free, and the "Softest contact bedding material available, providing maximum animal comfort" (quoted from Teklad) . The one down fall is that it has little odor control. For odor control I add a layer of Unscented Soft-Sorbent made by Kaytee on top of the Diamond Soft. While I don't like Kaytee as a company (to put it mildly), I do like this bedding. Soft Sorbent is made of wood fibers. It is soft to the touch yet not fluffy and as risky for impaction as some other beddings. It is also scent free (it doesn't smell like wood at all). It helps absorb odor and controls ammonia.
Food
I feed my mice a mix of 1/2 to 1/3 Sunseed Vita Hamster [Nutrient list] mixed with Regal rat made by Oxbow [Nutrient list].
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